rs1734595835

This variant is located in the NPY1R gene.

ClinVar annotation

Uncertain Significance☆☆☆
1 submitter

not specified

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About NPY1R

This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]

View all NPY1R variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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