rs1736135

This is a intergenic variant variant in the LOC101927745 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Crohn's disease

Barrett JC et al. “Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.” Nature Genetics 40(8):955-62 (2008)
Allele T
OR 1.18
p 7.0e-9
N 8,059
Large GWAS
European
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Research that mentions this SNP (1)

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Association between genome-wide association studies reported SNPs and pediatric-onset Crohn’s disease in Canadian children
AssociationN=1,116Devendra K. Amre et al.(2010)· Human Genetics

This case-control study of 563 Canadian children with pediatric-onset Crohn's disease and 553 controls confirmed associations between SNPs at two novel pediatric-specific loci (rs1250550 at 10q22.3, p=0.026; rs8049439 at 16p11.2, p=0.04) and disease susceptibility. Additionally, 6 of 16 previously reported adult CD loci were significantly associated with pediatric CD, demonstrating substantial genetic overlap between disease forms.

Traits studied:Crohn's diseaseInflammatory bowel disease
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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