rs179151
This variant is located in the SYNE3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
hair morphology
Luo J et al. “GWASs Identify Genetic Loci Associated with Human Scalp Hair Whorl Direction.” The Journal of Investigative Dermatology 143(10):2065-2068.e10 (2023)
Allele A
OR 1.11
p 6.0e-11
N 4,099
Large GWAS
East Asian
About SYNE3
Enables actin filament binding activity and cytoskeleton-nuclear membrane anchor activity. Involved in cytoskeleton organization; establishment of protein localization to membrane; and regulation of cell shape. Located in nuclear membrane. Part of meiotic nuclear membrane microtubule tethering complex. Biomarker of Huntington's disease. [provided by Alliance of Genome Resources, Jul 2025]
View all SYNE3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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