rs1792358

This is a intron variant variant in the FAT3 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

biological sex

Pirastu N et al. “Genetic analyses identify widespread sex-differential participation bias.” Nature Genetics 53(5):663-671 (2021)

Allele T

OR 0.01

p 4.0e-13

N 2,462,132

Large GWAS

European

About FAT3

Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within generation of neurons; negative regulation of dendrite development; and retina layer formation. Predicted to be located in dendrite and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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