rs182592259
This is a downstream gene variant variant in the ATG2B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
heart disease
Tängdén T et al. “A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections.” Scientific Reports 12(1):2582 (2022)
Allele A
OR 3.59
p 9.0e-9
N 337,484
Large GWAS
European
About ATG2B
This gene encodes a protein required for autophagy. The encoded protein is involved in autophagosome formation. A germline duplication of a region that includes this gene is associated with predisposition to myeloid malignancies. [provided by RefSeq, Jul 2016]
View all ATG2B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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