rs183627492

This is a intron variant variant in the ZNF277 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of Phosphatidylcholine (16:0_22:6) in blood serum

Tabassum R et al. Lipidome- and Genome-Wide Study to Understand Sex Differences in Circulatory Lipids. Journal of the American Heart Association 11(19):e027103 (2022)
Allele T
OR 0.87
p 1.0e-8
N 2,624
Large GWAS
European

About ZNF277

Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and zinc ion binding activity. Predicted to act upstream of or within cellular response to hydrogen peroxide and regulation of cellular senescence. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all ZNF277 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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