ZNF277
zinc finger protein 277
Summary
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and zinc ion binding activity. Predicted to act upstream of or within cellular response to hydrogen peroxide and regulation of cellular senescence. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants25 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs142246587 | 7:111,846,771 | A/G | — | likely benign |
| rs1244670013 | 7:111,846,788 | C/T | — | uncertain significance |
| rs747402620 | 7:111,846,845 | G/A | — | uncertain significance |
| rs1040348360 | 7:111,926,921 | A/T | — | likely benign |
| rs1449984619 | 7:111,926,924 | C/T | — | likely benign |
| rs747628267 | 7:111,926,954 | C/T | — | uncertain significance |
| rs151212296 | 7:111,926,979 | G/A | — | uncertain significance |
| rs761936072 | 7:111,926,997 | G/A | — | uncertain significance |
| rs1411068194 | 7:111,935,935 | A/T | — | uncertain significance |
| rs748077468 | 7:111,936,004 | C/G | — | uncertain significance |
| rs147613739 | 7:111,936,292 | G/A | — | conflicting classifications of pathogenicity |
| rs969589874 | 7:111,936,337 | C/T | — | uncertain significance |
| rs183627492 | 7:111,956,981 | G/T | intron variant | — |
| rs138489628 | 7:111,958,266 | A/G | — | likely benign |
| rs200160511 | 7:111,958,280 | A/G | — | likely benign |
| rs201172958 | 7:111,970,212 | C/T | — | uncertain significance |
| rs146166040 | 7:111,970,228 | C/G | — | uncertain significance |
| rs1429592862 | 7:111,976,195 | G/T | — | uncertain significance |
| rs760372336 | 7:111,977,790 | G/C | — | uncertain significance |
| rs1218205487 | 7:111,977,819 | G/T | — | uncertain significance |
| rs769635290 | 7:111,979,910 | T/C | — | uncertain significance |
| rs2486357774 | 7:111,980,991 | A/T | — | uncertain significance |
| rs773952287 | 7:111,981,052 | A/G | — | likely benign |
| rs758853594 | 7:111,981,087 | G/A | — | likely benign |
| rs552158554 | 7:111,984,121 | G/A | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.