rs552158554

This variant is located in the ZNF277 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cellulitis, abscess

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 2.01
p 9.0e-12
N 622,492
Major Consortium StudyLarge GWAS
multi-ancestry

About ZNF277

Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and zinc ion binding activity. Predicted to act upstream of or within cellular response to hydrogen peroxide and regulation of cellular senescence. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all ZNF277 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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