rs185551108
This variant is located in the PDYN gene.
▶ClinVar annotation
not specified; not provided; Spinocerebellar ataxia type 23; Inborn genetic diseases
View on ClinVar →About PDYN
The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
View all PDYN variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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