rs187540743
This is a intron variant variant in the ST18 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
response to antihypertensive drug
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 6.39
p 3.0e-12
N 568,095
Major Consortium StudyLarge GWAS
multi-ancestry
About ST18
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cytokine-mediated signaling pathway; negative regulation of cell population proliferation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of protein-DNA complex. [provided by Alliance of Genome Resources, Jul 2025]
View all ST18 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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