ST18
ST18 C2H2C-type zinc finger transcription factor
Summary
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cytokine-mediated signaling pathway; negative regulation of cell population proliferation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of protein-DNA complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants71 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs199871643 | 8:53,025,768 | A/C | — | uncertain significance |
| rs2549864840 | 8:53,028,854 | T/C | — | uncertain significance |
| rs752763322 | 8:53,028,875 | G/A | — | uncertain significance |
| rs544004934 | 8:53,028,942 | C/G | — | uncertain significance |
| rs117471862 | 8:53,030,923 | G/T | — | benign |
| rs144073708 | 8:53,044,521 | C/T | — | uncertain significance |
| rs2550311775 | 8:53,044,552 | C/T | — | uncertain significance |
| rs971768088 | 8:53,044,598 | G/C | — | uncertain significance |
| rs150215313 | 8:53,044,665 | C/T | — | uncertain significance |
| rs975599641 | 8:53,045,645 | T/C | — | uncertain significance |
| rs144563077 | 8:53,045,680 | C/T | — | uncertain significance |
| rs2550355503 | 8:53,045,848 | C/T | — | uncertain significance |
| rs766851307 | 8:53,049,994 | C/T | — | uncertain significance |
| rs372902206 | 8:53,055,520 | T/A | — | uncertain significance |
| rs2055804576 | 8:53,055,550 | G/T | — | uncertain significance |
| rs376858481 | 8:53,062,315 | C/T | — | uncertain significance |
| rs181322200 | 8:53,062,374 | T/C | — | uncertain significance |
| rs2550653962 | 8:53,062,375 | A/G | — | uncertain significance |
| rs1586987830 | 8:53,062,392 | A/G | — | uncertain significance |
| rs143580028 | 8:53,062,395 | A/G | — | conflicting classifications of pathogenicity |
| rs150534855 | 8:53,062,405 | T/C | — | uncertain significance |
| rs777326874 | 8:53,062,471 | C/T | — | uncertain significance |
| rs2060689620 | 8:53,071,490 | G/A | — | uncertain significance |
| rs2060691033 | 8:53,071,492 | A/T | — | uncertain significance |
| rs759547900 | 8:53,071,517 | T/G | — | uncertain significance |
| rs181868806 | 8:53,071,574 | C/T | — | uncertain significance |
| rs749246680 | 8:53,071,595 | G/A | — | uncertain significance |
| rs765955856 | 8:53,071,655 | T/C | — | uncertain significance |
| rs1016952385 | 8:53,071,658 | G/A | — | likely benign |
| rs894006203 | 8:53,073,962 | C/T | — | uncertain significance |
| rs745820953 | 8:53,073,977 | T/C | — | likely benign |
| rs1464222305 | 8:53,073,980 | G/C | — | uncertain significance |
| rs749605288 | 8:53,073,992 | C/T | — | uncertain significance |
| rs138273457 | 8:53,074,015 | G/A | — | uncertain significance |
| rs2061436663 | 8:53,074,022 | C/T | — | uncertain significance |
| rs771306930 | 8:53,074,064 | T/C | — | uncertain significance |
| rs2550827905 | 8:53,074,099 | T/C | — | uncertain significance |
| rs2550865458 | 8:53,076,607 | A/G | — | uncertain significance |
| rs34326988 | 8:53,077,749 | G/A | — | uncertain significance |
| rs530029309 | 8:53,079,426 | C/T | — | uncertain significance |
| rs1398012258 | 8:53,079,465 | G/A | — | uncertain significance |
| rs983036670 | 8:53,084,435 | C/A | — | uncertain significance |
| rs1334524124 | 8:53,084,544 | C/A | — | uncertain significance |
| rs75439564 | 8:53,084,575 | A/G | — | benign |
| rs749557743 | 8:53,084,684 | C/A | — | uncertain significance |
| rs2550952163 | 8:53,084,826 | C/T | — | uncertain significance |
| rs372843576 | 8:53,084,885 | A/C | — | uncertain significance |
| rs747532843 | 8:53,084,941 | C/G | — | uncertain significance |
| rs754421796 | 8:53,084,956 | C/G | — | uncertain significance |
| rs2550958897 | 8:53,084,988 | C/T | — | likely benign |
| rs150133719 | 8:53,085,002 | A/G | — | likely benign |
| rs373262592 | 8:53,085,056 | T/A | — | uncertain significance |
| rs768616435 | 8:53,085,059 | C/G | — | uncertain significance |
| rs2550962958 | 8:53,085,121 | C/A | — | uncertain significance |
| rs200508606 | 8:53,092,739 | G/A | — | uncertain significance |
| rs369367169 | 8:53,092,756 | G/C | — | uncertain significance |
| rs764698287 | 8:53,092,850 | C/T | — | uncertain significance |
| rs199766596 | 8:53,092,852 | A/G | — | uncertain significance |
| rs1364494801 | 8:53,124,667 | G/T | — | uncertain significance |
| rs374865783 | 8:53,126,764 | C/G | — | uncertain significance |
| rs11988076 | 8:53,128,629 | A/G | intron variant | — |
| rs7845620 | 8:53,129,069 | A/C | intron variant | — |
| rs2304365 | 8:53,130,213 | C/T | intron variant | — |
| rs62501032 | 8:53,135,632 | G/A | intron variant | — |
| rs4074067 | 8:53,137,329 | C/T | intron variant | — |
| rs187540743 | 8:53,141,987 | C/G | intron variant | — |
| rs16917562 | 8:53,162,201 | A/T | intron variant | — |
| rs10504140 | 8:53,202,675 | C/T | upstream gene variant | — |
| rs7009219 | 8:53,214,265 | C/G | — | — |
| rs74423717 | 8:53,229,336 | T/A | upstream gene variant | — |
| rs183567001 | 8:53,286,471 | C/T | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.