rs1878406
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
pulse pressure measurement
Hoffmann TJ et al. “Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.” Nature Genetics 49(1):54-64 (2017)
Allele C
OR 0.29
p 4.0e-16
N 321,262
Large GWAS
multi-ancestry
atherosclerosis
Bis JC et al. “Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.” Nature Genetics 43(10):940-7 (2011)
Allele T
OR 0.20
p 7.0e-12
N 31,211
Meta-analysisMajor Consortium StudyLarge GWAS
multi-ancestry
large artery stroke
Mishra A et al. “Stroke genetics informs drug discovery and risk prediction across ancestries.” Nature 611(7934):115-123 (2022)
Allele T
OR 1.08
p 1.0e-9
N 1,241,207
Large GWAS
European
systolic blood pressure
Hoffmann TJ et al. “Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.” Nature Genetics 49(1):54-64 (2017)
Allele C
OR 0.32
p 2.0e-9
N 321,262
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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