rs188599171
This variant is located in the CUX1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Ischemic stroke
Earley EJ et al. “Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci.” British Journal of Haematology 201(2):343-352 (2023)
Allele A
OR 5.60
p 6.0e-11
N 1,333
Large GWAS
Hispanic or Latin American
About CUX1
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]
View all CUX1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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