rs188937806
This is a intron variant variant in the PARD3B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
hypertrophic cardiomyopathy
Gyftopoulos A et al. “Identification of Novel Genetic Variants and Comorbidities Associated With ICD-10-Based Diagnosis of Hypertrophic Cardiomyopathy Using the UK Biobank Cohort.” Frontiers in Genetics 13:866042 (2022)
Allele T
OR 3.80
p 1.0e-8
N 7,623
Major Consortium StudyLarge GWAS
multi-ancestry
About PARD3B
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in several processes, including establishment of cell polarity; establishment of centrosome localization; and establishment or maintenance of epithelial cell apical/basal polarity. Located in cell junction. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]
View all PARD3B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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