PARD3B

par-3 family cell polarity regulator beta

Summary

Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in several processes, including establishment of cell polarity; establishment of centrosome localization; and establishment or maintenance of epithelial cell apical/basal polarity. Located in cell junction. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants114 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs980990963	2:205,410,739	G/A	—	uncertain significance
rs765823995	2:205,410,777	G/A	—	uncertain significance
rs1019357	2:205,535,918	C/G	intron variant	—
rs1486027366	2:205,550,928	C/G	—	uncertain significance
rs188923583	2:205,550,933	C/T	—	benign
rs559681044	2:205,734,003	A/G	—	—
rs148776266	2:205,748,294	A/C	intron variant	—
rs188937806	2:205,754,718	C/T	intron variant	—
rs1469048315	2:205,829,915	T/C	—	uncertain significance
rs2469295134	2:205,829,984	A/G	—	uncertain significance
rs74648966	2:205,830,017	T/C	—	likely benign
rs1238050752	2:205,830,026	C/A	—	uncertain significance
rs772515904	2:205,830,029	C/T	—	uncertain significance
rs1691138075	2:205,830,031	T/A	—	uncertain significance
rs2335704	2:205,864,832	C/A	intron variant	—
rs375051020	2:205,912,372	G/A	—	uncertain significance
rs191906362	2:205,912,387	G/A	—	uncertain significance
rs374453548	2:205,969,157	C/T	—	uncertain significance
rs769820507	2:205,978,229	C/A	—	uncertain significance
rs775487298	2:205,978,236	G/T	—	uncertain significance
rs776220094	2:205,983,697	G/A	—	uncertain significance
rs2030288005	2:205,983,709	C/T	—	uncertain significance
rs368878317	2:205,983,712	G/A	—	uncertain significance
rs756939866	2:205,983,751	G/A	—	uncertain significance
rs750051754	2:205,983,759	A/C	—	uncertain significance
rs2469265730	2:205,986,329	T/C	—	uncertain significance
rs756173188	2:205,986,350	C/A	—	uncertain significance
rs548396478	2:205,986,361	C/T	—	uncertain significance
rs770492830	2:205,986,367	G/A	—	uncertain significance
rs369451984	2:205,986,392	A/G	—	uncertain significance
rs751420352	2:205,986,394	T/G	—	uncertain significance
rs34751010	2:205,986,458	A/T	—	uncertain significance
rs761545852	2:205,986,460	G/T	—	uncertain significance
rs201552655	2:205,986,509	C/T	—	uncertain significance
rs1277484824	2:205,986,569	G/A	—	uncertain significance
rs765443472	2:205,986,605	C/T	—	uncertain significance
rs770806856	2:205,986,671	A/G	—	uncertain significance
rs201211082	2:205,989,107	G/A	—	uncertain significance
rs368896954	2:205,989,110	C/T	—	uncertain significance
rs751207163	2:205,990,358	G/A	—	uncertain significance
rs767186465	2:205,990,360	A/G	—	uncertain significance
rs912391300	2:205,990,408	A/G	—	uncertain significance
rs1218525422	2:205,990,426	G/A	—	uncertain significance
rs12477797	2:205,991,157	G/A	intron variant	—
rs62172701	2:205,998,191	A/C	intron variant	—
rs12466813	2:206,000,607	C/A	—	—
rs10180371	2:206,014,979	A/G	—	—
rs1439059324	2:206,023,621	C/A	—	uncertain significance
rs148818018	2:206,036,948	G/A	—	uncertain significance
rs1380952373	2:206,036,954	A/G	—	uncertain significance
rs753102493	2:206,036,986	C/T	—	uncertain significance
rs755830374	2:206,037,007	G/A	—	uncertain significance
rs555529295	2:206,037,013	A/T	—	uncertain significance
rs773211664	2:206,037,035	T/C	—	uncertain significance
rs35911047	2:206,040,623	G/A	—	—
rs368676695	2:206,041,197	A/G	—	uncertain significance
rs1360182820	2:206,041,259	C/A	—	uncertain significance
rs201299201	2:206,041,262	C/T	—	uncertain significance
rs755488656	2:206,050,508	G/A	—	uncertain significance
rs768435807	2:206,050,545	C/T	—	uncertain significance
rs10153620	2:206,060,637	G/T	—	—
rs11681930	2:206,063,298	G/A	regulatory region variant	—
rs4675502	2:206,086,171	G/C	—	—
rs4675503	2:206,086,249	T/C	intron variant	—
rs1207421	2:206,150,594	A/G	intron variant	—
rs747249162	2:206,165,287	G/A	—	uncertain significance
rs928737378	2:206,165,375	G/A	—	likely benign
rs2470421246	2:206,165,450	A/C	—	uncertain significance
rs377142288	2:206,166,247	C/T	—	uncertain significance
rs2470426989	2:206,166,268	G/A	—	uncertain significance
rs1392124236	2:206,166,271	G/A	—	uncertain significance
rs374843237	2:206,166,305	C/T	—	uncertain significance
rs919457776	2:206,166,334	G/A	—	uncertain significance
rs781674638	2:206,166,361	C/A	—	uncertain significance
rs202062600	2:206,166,362	G/T	—	uncertain significance
rs761178202	2:206,166,364	A/C	—	uncertain significance
rs765315815	2:206,166,396	A/G	—	uncertain significance
rs849230	2:206,261,029	G/T	—	—
rs2468992136	2:206,265,766	G/T	—	uncertain significance
rs201236501	2:206,265,838	A/G	—	likely benign
rs74341236	2:206,305,134	A/G	—	uncertain significance
rs143299684	2:206,305,146	G/A	—	uncertain significance
rs376842250	2:206,305,196	A/C	—	uncertain significance
rs1240190865	2:206,305,231	G/A	—	uncertain significance
rs752726864	2:206,305,273	C/T	—	uncertain significance
rs1409510128	2:206,305,300	C/G	—	uncertain significance
rs199699507	2:206,305,302	C/T	—	uncertain significance
rs2047680377	2:206,305,332	G/C	—	uncertain significance
rs375164744	2:206,305,394	C/T	—	uncertain significance
rs11884476	2:206,318,593	C/G	intron variant	—
rs868232958	2:206,364,641	C/A	—	uncertain significance
rs375059681	2:206,364,664	G/A	—	uncertain significance
rs201666772	2:206,364,717	G/A	—	uncertain significance
rs2469911602	2:206,418,061	G/A	—	uncertain significance
rs930720504	2:206,418,066	G/C	—	uncertain significance
rs2106496926	2:206,418,078	C/T	—	uncertain significance
rs201558826	2:206,418,087	C/T	—	uncertain significance
rs572403823	2:206,418,088	G/A	—	uncertain significance
rs749592923	2:206,418,107	G/T	—	uncertain significance
rs368688012	2:206,418,114	G/A	—	uncertain significance

Showing 100 of 114 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.