rs2335704
This is a intron variant variant in the PARD3B gene.
▶Research that mentions this SNP (1)
▶Association of polymorphisms in the Chr18q11.2 locus with tuberculosis in Chinese populationAssociationN=2,665Xingyan Wang et al.(2013)· Human Genetics
Replication study of two TB susceptibility SNPs (rs4331426 and rs2335704) identified in African populations. In a cohort of 1,385 Chinese TB cases and 1,280 controls, only rs4331426 showed significant association (p=0.011), but with opposite effect direction: the G allele was protective in Chinese (OR=0.62, 95% CI 0.44-0.87) versus risk-increasing in African populations (OR=1.19, 95% CI 1.12-1.26). No significant association was found for rs2335704 (p=0.91).
About PARD3B
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in several processes, including establishment of cell polarity; establishment of centrosome localization; and establishment or maintenance of epithelial cell apical/basal polarity. Located in cell junction. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]
View all PARD3B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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