rs1898349
This variant is located in the SHTN1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
cleft lip
Dack K et al. “Genetic heterogeneity and homogeneity among orofacial cleft subtypes: genome-wide association studies in the cleft collective.” Human Molecular Genetics 34(23):1934-1950 (2025)
Allele T
OR 1.39
p 9.0e-9
N 8,997
Large GWAS
European
About SHTN1
Enables identical protein binding activity. Involved in positive regulation of neuron migration. Located in cytoplasm and microtubule. [provided by Alliance of Genome Resources, Jul 2025]
View all SHTN1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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