rs190692818

This is a regulatory region variant variant in the SFMBT2 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

nephrotic syndrome

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 4.01
p 1.0e-11
N 631,243
Major Consortium StudyLarge GWAS
multi-ancestry

About SFMBT2

Enables histone binding activity. Involved in negative regulation of gene expression. Located in aggresome; cytosol; and nuclear speck. [provided by Alliance of Genome Resources, Jul 2025]

View all SFMBT2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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