SFMBT2
Scm like with four mbt domains 2
Summary
Enables histone binding activity. Involved in negative regulation of gene expression. Located in aggresome; cytosol; and nuclear speck. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants53 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs200854532 | 10:7,205,767 | C/G | — | uncertain significance |
| rs760060335 | 10:7,205,826 | T/C | — | uncertain significance |
| rs142215982 | 10:7,213,000 | C/T | — | uncertain significance |
| rs760174479 | 10:7,213,868 | C/T | — | uncertain significance |
| rs377047427 | 10:7,213,925 | C/T | — | likely benign |
| rs768081251 | 10:7,213,948 | G/A | — | uncertain significance |
| rs777199910 | 10:7,213,960 | C/A | — | uncertain significance |
| rs541625810 | 10:7,213,961 | G/A | — | uncertain significance |
| rs775887528 | 10:7,213,964 | C/T | — | uncertain significance |
| rs376646980 | 10:7,214,000 | G/A | — | uncertain significance |
| rs767676222 | 10:7,214,029 | G/A | — | uncertain significance |
| rs930256087 | 10:7,214,059 | G/C | — | uncertain significance |
| rs2491045016 | 10:7,214,060 | A/G | — | uncertain significance |
| rs138413440 | 10:7,214,462 | C/T | — | uncertain significance |
| rs774454869 | 10:7,214,483 | C/T | — | uncertain significance |
| rs201323474 | 10:7,214,506 | T/C | — | uncertain significance |
| rs374674288 | 10:7,214,510 | C/G | — | uncertain significance |
| rs370491896 | 10:7,214,525 | G/A | — | uncertain significance |
| rs1415368617 | 10:7,214,527 | C/T | — | uncertain significance |
| rs748712257 | 10:7,214,543 | C/A | — | uncertain significance |
| rs535158127 | 10:7,214,564 | C/T | — | uncertain significance |
| rs770902493 | 10:7,218,011 | G/A | — | uncertain significance |
| rs1228103064 | 10:7,218,024 | T/G | — | uncertain significance |
| rs766994102 | 10:7,218,032 | C/G | — | uncertain significance |
| rs150573223 | 10:7,218,086 | C/T | — | uncertain significance |
| rs145294864 | 10:7,218,090 | C/T | — | uncertain significance |
| rs1449619307 | 10:7,218,126 | A/G | — | uncertain significance |
| rs145231461 | 10:7,239,527 | C/T | — | uncertain significance |
| rs200366842 | 10:7,239,644 | C/T | — | uncertain significance |
| rs41306802 | 10:7,244,434 | G/A | — | benign |
| rs199572509 | 10:7,247,858 | C/T | — | uncertain significance |
| rs141326530 | 10:7,247,863 | A/G | — | uncertain significance |
| rs558098039 | 10:7,254,189 | T/C | — | — |
| rs537237202 | 10:7,262,064 | T/C | — | — |
| rs138425580 | 10:7,262,415 | C/T | — | uncertain significance |
| rs768302535 | 10:7,262,490 | T/C | — | uncertain significance |
| rs757058342 | 10:7,269,849 | C/T | — | likely benign |
| rs762601453 | 10:7,269,890 | C/T | — | uncertain significance |
| rs761046317 | 10:7,285,536 | G/A | — | likely benign |
| rs370903594 | 10:7,290,548 | A/G | — | uncertain significance |
| rs770614042 | 10:7,290,572 | T/C | — | uncertain significance |
| rs117741182 | 10:7,290,605 | C/T | — | likely benign |
| rs190692818 | 10:7,299,343 | T/C | regulatory region variant | — |
| rs1235065447 | 10:7,325,892 | T/C | — | uncertain significance |
| rs1306399745 | 10:7,325,965 | C/T | — | uncertain significance |
| rs137982565 | 10:7,409,686 | A/T | — | uncertain significance |
| rs777305791 | 10:7,409,751 | G/A | — | uncertain significance |
| rs759290525 | 10:7,409,832 | C/T | — | uncertain significance |
| rs1463605866 | 10:7,412,310 | C/A | — | uncertain significance |
| rs1845028225 | 10:7,412,325 | C/A | — | uncertain significance |
| rs144185734 | 10:7,423,829 | T/G | — | uncertain significance |
| rs1318394764 | 10:7,423,835 | T/C | — | likely benign |
| rs12356750 | 10:7,450,221 | G/C | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.