rs1948915
This variant is located in the CCAT1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
multiple myeloma
Went M et al. “Deciphering the genetics and mechanisms of predisposition to multiple myeloma.” Nature Communications 15(1):6644 (2024)
Allele C
OR 1.15
p 2.0e-15
N 377,127
Large GWAS
European
Mitchell JS et al. “Genome-wide association study identifies multiple susceptibility loci for multiple myeloma.” Nature Communications 7:12050 (2016)
Allele C
OR 1.13
p 4.0e-11
N 241,704
Large GWAS
European
About CCAT1
This gene produces a long non-coding RNA that promotes tumor formation and is upregulated in colon cancer and other cancer cell types. This transcript may regulate long range chromosomal interactions, including at the Myc oncoprotein locus. This RNA may also function as a molecular sponge for microRNAs. [provided by RefSeq, Dec 2017]
View all CCAT1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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