Trait
SNPs associated with Multiple myeloma
75 genetic variants across 25 genes have been associated with Multiple myeloma in published research. Key genes include ANXA13, ATG5, BRCA2.
Associated variants75 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1544410 | VDR | Increased multiple myeloma risk in Asian populations | Meta-analysis |
| rs2228570 | VDR | Increased multiple myeloma risk | Meta-analysis |
| rs34562254 | TNFRSF13B | GWAS association (p=3.0e-23) | Major Consortium Study |
| rs4792800 | TNFRSF13B | GWAS association (p=8.0e-13) | Major Consortium Study |
| rs1003099744 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs534109572 | NRG3 | GWAS association (p=8.0e-12) | Major Consortium Study |
| rs142614314 | ANXA13 | GWAS association (p=9.0e-12) | Major Consortium Study |
| rs181591697 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs75341503 | — | GWAS association (p=1.0e-35) | Large GWAS |
| rs5995688 | CBX7 | GWAS association (p=3.0e-31) | Large GWAS |
| rs7577599 | DTNB | GWAS association (p=8.0e-28) | Large GWAS |
| rs139402 | CBX7 | GWAS association (p=5.0e-26) | Large GWAS |
| rs3132535 | CCHCR1 | GWAS association (p=2.0e-22) | Large GWAS |
| rs6546615 | — | GWAS association (p=7.0e-22) | Large GWAS |
| rs9856633 | — | GWAS association (p=2.0e-20) | Large GWAS |
| rs10233479 | — | GWAS association (p=5.0e-19) | Large GWAS |
| rs6599192 | ULK4 | GWAS association (p=9.0e-18) | Large GWAS |
| rs7621631 | — | GWAS association (p=9.0e-18) | Large GWAS |
| rs9386514 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs3731222 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs877529 | CBX7 | GWAS association (p=8.0e-16) | Large GWAS |
| rs1948915 | CCAT1 | GWAS association (p=2.0e-15) | Large GWAS |
| rs4487645 | DNAH11 | GWAS association (p=3.0e-14) | Large GWAS |
| rs10936600 | LRRC34 | GWAS association (p=6.0e-15) | Large GWAS |
| rs9372120 | ATG5 | GWAS association (p=9.0e-15) | Large GWAS |
| rs4273077 | TNFRSF13B | GWAS association (p=3.0e-14) | Large GWAS |
| rs10936599 | MYNN | GWAS association (p=9.0e-14) | Large GWAS |
| rs6066835 | PREX1 | GWAS association (p=1.0e-13) | Large GWAS |
| rs13338946 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs2811710 | CDKN2A | GWAS association (p=2.0e-13) | Large GWAS |
| rs11085015 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs6090899 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs11744881 | ELL2 | GWAS association (p=6.0e-13) | Large GWAS |
| rs11762574 | — | GWAS association (p=8.0e-13) | Large GWAS |
| rs8058928 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs7193541 | RFWD3 | GWAS association (p=5.0e-12) | Large GWAS |
| rs200203825 | — | GWAS association (p=8.0e-12) | Large GWAS |
| rs2285803 | PSORS1C1 | GWAS association (p=1.0e-11) | Large GWAS |
| rs1423269 | ELL2 | GWAS association (p=2.0e-11) | Large GWAS |
| rs10746812 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs57968458 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs11086029 | KLF2 | GWAS association (p=7.0e-11) | Large GWAS |
| rs6746082 | DTNB | GWAS association (p=2.0e-10) | Large GWAS |
| rs7781265 | SMARCD3 | GWAS association (p=3.0e-10) | Large GWAS |
| rs75712673 | SOHLH2 | GWAS association (p=3.0e-10) | Large GWAS |
| rs6919908 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs4808046 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs2993984 | — | GWAS association (p=7.0e-10) | Large GWAS |
| rs3737315 | — | GWAS association (p=8.0e-10) | Large GWAS |
| rs8050262 | — | GWAS association (p=8.0e-10) | Large GWAS |
| rs6599175 | ULK4 | GWAS association (p=1.0e-09) | Large GWAS |
| rs11813268 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs56219066 | ELL2 | GWAS association (p=1.0e-09) | Large GWAS |
| rs2272007 | ULK4 | GWAS association (p=2.0e-09) | Large GWAS |
| rs139371 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs77033531 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs34565965 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs2822736 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs1052501 | ULK4 | GWAS association (p=2.0e-08) | Large GWAS |
| rs16862227 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs2162826 | — | GWAS association (p=7.0e-09) | Large GWAS |
| rs4325816 | — | GWAS association (p=7.0e-09) | Large GWAS |
| rs17507636 | — | GWAS association (p=9.0e-09) | Large GWAS |
| rs34229995 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs6595443 | CEP120 | GWAS association (p=1.0e-08) | Large GWAS |
| rs56179914 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs2790457 | WAC | GWAS association (p=2.0e-08) | Large GWAS |
| rs6864880 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs1050976 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs138747 | TOM1 | GWAS association (p=3.0e-08) | Large GWAS |
| rs11571833 | BRCA2 | GWAS association (p=3.0e-08) | Large GWAS |
| rs58618031 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs57104699 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs8107139 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs603965 | — | GWAS association (p=2.0e-11) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.