rs5995688

This is a regulatory region variant variant in the CBX7 gene.

▶

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

multiple myeloma

Went M et al. “Deciphering the genetics and mechanisms of predisposition to multiple myeloma.” Nature Communications 15(1):6644 (2024)

Allele G

OR 1.21

p 3.0e-31

N 377,127

Large GWAS

European

About CBX7

This gene encodes a protein that contains the CHROMO (CHRomatin Organization MOdifier) domain. The encoded protein is a component of the Polycomb repressive complex 1 (PRC1), and is thought to control the lifespan of several normal human cells. [provided by RefSeq, Oct 2016]

View all CBX7 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…