rs2285803
This is a downstream gene variant variant in the PSORS1C1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
multiple myeloma
Duran-Lozano L et al. “Germline variants at SOHLH2 influence multiple myeloma risk.” Blood Cancer Journal 11(4):76 (2021)
Allele T
OR 1.17
p 1.0e-11
N 350,263
Large GWAS
European
Chubb D et al. “Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.” Nature Genetics 45(10):1221-1225 (2013)
Allele T
OR 1.19
p 1.0e-10
N 9,641
Large GWAS
European
BMI-adjusted waist-hip ratio
Christakoudi S et al. “GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.” Scientific Reports 11(1):10688 (2021)
Allele T
OR 0.02
p 3.0e-8
N 219,872
Major Consortium StudyLarge GWAS
European
About PSORS1C1
This gene is one of several genes thought to confer susceptibility to psoriasis and systemic sclerosis, located on chromosome 6 near the major histocompatibility complex (MHC) class I region. [provided by RefSeq, Sep 2011]
View all PSORS1C1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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