ULK4
unc-51 like kinase 4
Summary
This gene encodes a member of the unc-51-like serine/threonine kinase (STK) family. Members of this protein family play a role in neuronal growth and endocytosis. The encoded protein is likely involved in neurite branching, neurite elongation and neuronal migration. Genome-wide association studies (GWAS) indicate an association of variations in this gene with blood pressure and hypertension. Sequence variations in this gene may also be be associated with psychiatric disorders, including schizophrenia and bipolar disorder. Pseudogenes associated with this gene have been identified and are located on chromosome 15. [provided by RefSeq, Jul 2016]
Known Variants173 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs754890627 | 3:41,288,431 | C/T | — | uncertain significance |
| rs372547665 | 3:41,288,467 | C/T | — | uncertain significance |
| rs202237555 | 3:41,288,472 | T/C | — | uncertain significance |
| rs773925415 | 3:41,290,982 | A/T | — | uncertain significance |
| rs774024992 | 3:41,290,992 | G/A | — | uncertain significance |
| rs767209232 | 3:41,290,999 | G/A | — | uncertain significance |
| rs763985605 | 3:41,291,011 | G/A | — | uncertain significance |
| rs6781242 | 3:41,300,601 | A/G | intron variant | — |
| rs9852315 | 3:41,340,824 | A/G | intron variant | — |
| rs9867802 | 3:41,343,555 | A/C | intron variant | — |
| rs776360482 | 3:41,439,628 | A/G | — | uncertain significance |
| rs374358758 | 3:41,439,646 | T/C | — | uncertain significance |
| rs754228128 | 3:41,439,674 | G/A | — | uncertain significance |
| rs2082104511 | 3:41,439,677 | T/C | — | uncertain significance |
| rs367582738 | 3:41,439,688 | T/C | — | uncertain significance |
| rs766254000 | 3:41,439,733 | A/G | — | uncertain significance |
| rs2471440295 | 3:41,497,026 | T/C | — | uncertain significance |
| rs371028369 | 3:41,497,038 | G/C | — | uncertain significance |
| rs142834126 | 3:41,497,069 | T/C | — | benign |
| rs752231053 | 3:41,497,076 | G/C | — | uncertain significance |
| rs560135771 | 3:41,504,597 | A/G | — | uncertain significance |
| rs1461995321 | 3:41,504,655 | G/C | — | likely benign |
| rs200243418 | 3:41,504,721 | G/A | — | likely benign |
| rs1691951 | 3:41,568,658 | T/A | — | — |
| rs79796449 | 3:41,579,562 | T/C | intron variant | — |
| rs2471757629 | 3:41,607,524 | T/A | — | uncertain significance |
| rs2471757754 | 3:41,607,537 | T/C | — | uncertain significance |
| rs143473972 | 3:41,607,541 | C/T | — | likely benign |
| rs778926591 | 3:41,607,557 | A/T | — | uncertain significance |
| rs373580662 | 3:41,607,583 | A/C | — | uncertain significance |
| rs760559778 | 3:41,607,620 | T/A | — | uncertain significance |
| rs1204607060 | 3:41,657,207 | G/A | — | uncertain significance |
| rs371671274 | 3:41,705,128 | G/A | — | uncertain significance |
| rs747942093 | 3:41,705,163 | G/C | — | uncertain significance |
| rs200586304 | 3:41,705,176 | A/G | — | uncertain significance |
| rs373263389 | 3:41,723,035 | T/C | — | likely benign |
| rs2035924129 | 3:41,723,087 | T/C | — | uncertain significance |
| rs188590896 | 3:41,723,090 | C/T | — | likely benign |
| rs760046506 | 3:41,723,119 | C/T | — | uncertain significance |
| rs201806676 | 3:41,723,128 | A/G | — | uncertain significance |
| rs201639701 | 3:41,746,550 | G/A | — | uncertain significance |
| rs1163625943 | 3:41,746,590 | T/A | — | uncertain significance |
| rs2470670129 | 3:41,746,615 | C/A | — | uncertain significance |
| rs565139607 | 3:41,746,766 | G/A | — | uncertain significance |
| rs61650641 | 3:41,746,783 | A/G | — | likely benign |
| rs6763508 | 3:41,750,989 | T/C | intron variant | — |
| rs199884004 | 3:41,756,779 | G/A | — | likely benign |
| rs373340083 | 3:41,756,950 | C/G | — | uncertain significance |
| rs61744388 | 3:41,756,965 | C/T | — | benign |
| rs371069374 | 3:41,756,975 | G/A | — | likely benign |
| rs199600821 | 3:41,756,984 | C/T | — | likely benign |
| rs61744385 | 3:41,756,986 | A/T | — | benign |
| rs1279345039 | 3:41,756,991 | A/C | — | uncertain significance |
| rs555915240 | 3:41,757,025 | G/C | — | uncertain significance |
| rs751099860 | 3:41,757,055 | T/A | — | uncertain significance |
| rs200463650 | 3:41,759,262 | G/A | — | uncertain significance |
| rs771337091 | 3:41,759,287 | A/G | — | likely benign |
| rs763880036 | 3:41,759,329 | G/C | — | uncertain significance |
| rs7651190 | 3:41,765,955 | A/G | intron variant | — |
| rs6599175 | 3:41,786,009 | T/C | intron variant | — |
| rs73069394 | 3:41,787,233 | G/A | intron variant | — |
| rs6599176 | 3:41,788,492 | T/G | intron variant | — |
| rs202201652 | 3:41,795,901 | T/A | — | uncertain significance |
| rs200312148 | 3:41,795,902 | A/G | — | uncertain significance |
| rs1235536360 | 3:41,795,916 | A/G | — | uncertain significance |
| rs192020899 | 3:41,795,957 | A/G | — | likely benign |
| rs1169782394 | 3:41,795,965 | T/C | — | likely benign |
| rs9311288 | 3:41,804,581 | C/T | — | — |
| rs9837273 | 3:41,813,104 | T/C | upstream gene variant | — |
| rs9817510 | 3:41,813,108 | C/G | — | — |
| rs10452022 | 3:41,816,042 | G/T | — | — |
| rs7644787 | 3:41,818,108 | A/G | intron variant | — |
| rs10212536 | 3:41,827,026 | A/C | — | — |
| rs73071352 | 3:41,828,300 | A/G | intron variant | — |
| rs2470917523 | 3:41,831,164 | T/G | — | uncertain significance |
| rs17215589 | 3:41,831,203 | C/T | — | benign |
| rs77615850 | 3:41,831,290 | C/T | — | likely benign |
| rs1362306553 | 3:41,831,325 | C/T | — | uncertain significance |
| rs13324552 | 3:41,837,977 | G/A | intron variant | — |
| rs2371627 | 3:41,839,219 | A/G | intron variant | — |
| rs4621303 | 3:41,839,370 | T/G | — | — |
| rs4973986 | 3:41,841,716 | C/A | — | benign |
| rs9811247 | 3:41,847,353 | G/T | — | — |
| rs373288921 | 3:41,847,736 | G/C | — | — |
| rs17063572 | 3:41,860,955 | A/G | — | benign |
| rs1259220051 | 3:41,860,977 | T/C | — | uncertain significance |
| rs751629337 | 3:41,860,980 | G/T | — | uncertain significance |
| rs7649989 | 3:41,865,843 | A/G | — | — |
| rs200308031 | 3:41,867,599 | T/G | — | — |
| rs143471145 | 3:41,867,613 | A/T | intron variant | — |
| rs35475272 | 3:41,867,643 | T/G | — | — |
| rs111836980 | 3:41,867,736 | A/C | intron variant | — |
| rs540812816 | 3:41,868,076 | G/A | — | — |
| rs144418074 | 3:41,868,280 | A/T | intron variant | — |
| rs111821658 | 3:41,870,466 | C/T | — | — |
| rs374164869 | 3:41,870,743 | G/C | — | — |
| rs182702766 | 3:41,870,971 | G/A | — | — |
| rs541051407 | 3:41,871,295 | G/C | — | — |
| rs111634789 | 3:41,871,356 | T/G | — | — |
| rs28581706 | 3:41,871,397 | A/T | — | — |
Showing 100 of 173 variants. Use the SNP search for the full list.
Gene information from NCBI Gene. Variant classifications from ClinVar.