rs3731222

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

multiple myeloma

Went M et al. “Deciphering the genetics and mechanisms of predisposition to multiple myeloma.” Nature Communications 15(1):6644 (2024)
Allele T
OR 1.23
p 3.0e-16
N 377,127
Large GWAS
European
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Research that mentions this SNP (1)

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Strong association of common variants in the CDKN2A/CDKN2B region with type 2 diabetes in French Europids
AssociationN=3,093Duesing K. et al.(2008)· Diabetologia

A replication study of genome-wide association findings in the CDKN2A/CDKN2B region on chromosome 9p in 3,093 French Europids (1,455 cases, 1,638 controls). The study confirms a strong association of rs10811661 with type 2 diabetes (p=3.8×10⁻⁷, OR 1.43 [95% CI 1.24-1.64]) and identifies rs3218018 as a secondary signal surviving Bonferroni correction (p=0.002). The rs564398 variant did not reach significance in this population.

Traits studied:Type 2 diabetes
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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