rs1975484
This is a intron variant variant in the PPP4R3B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
total cholesterol measurement
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele A
OR 0.01
p 7.0e-9
N 928,679
Large GWAS
multi-ancestry
About PPP4R3B
Predicted to enable protein phosphatase activator activity. Involved in regulation of double-strand break repair. Located in centrosome; chromatin; and nuclear speck. Part of protein phosphatase 4 complex. [provided by Alliance of Genome Resources, Jul 2025]
View all PPP4R3B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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