rs1997997
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
QT interval
Young WJ et al. “Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.” Nature Communications 13(1):5144 (2022)
Allele A
OR 0.02
p 4.0e-15
N 252,730
Large GWAS
European, African unspecified, Hispanic or Latin American, South East Asian, South Asian
heart failure
Levin MG et al. “Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure.” Nature Communications 13(1):6914 (2022)
Allele A
OR 0.03
p 4.0e-11
N 1,665,481
Large GWAS
multi-ancestry
Enzan N et al. “Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population.” Nature Communications 16(1):9680 (2025)
Allele A
OR 0.03
p 2.0e-8
N 1,672,415
Large GWAS
multi-ancestry
QRS-T angle
Young WJ et al. “Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.” Nature Communications 14(1):1411 (2023)
Allele A
OR 0.02
p 2.0e-8
N 159,715
Large GWAS
European, African unspecified, Hispanic or Latin American
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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