rs200742383
This variant is located in the TMEM270 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
response to antihypertensive drug
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 2.37
p 2.0e-13
N 568,095
Major Consortium StudyLarge GWAS
multi-ancestry
poisoning
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 2.15
p 3.0e-13
N 565,659
Major Consortium StudyLarge GWAS
multi-ancestry
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitterAbout TMEM270
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all TMEM270 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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