rs201213870

This variant is located in the ENPEP gene.

ClinVar annotation

Uncertain Significance☆☆☆
1 submitter

not specified

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About ENPEP

The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19. [provided by RefSeq, Apr 2020]

View all ENPEP variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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