rs201338035

This variant is located in the ADRB3 gene.

ClinVar annotation

Uncertain Significance☆☆☆
1 submitter

not specified

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About ADRB3

The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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