rs2075571

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of folate receptor alpha in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.04
p 8.0e-16
N 47,745
Large GWAS
European

gout

Major TJ et al. “A genome-wide association analysis reveals new pathogenic pathways in gout.” Nature Genetics 56(11):2392-2406 (2024)
Allele T
OR 0.94
p 1.0e-9
N 1,195,362
Large GWAS
European

body height

Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele C
OR 0.01
p 4.0e-9
N 405,540
Large GWAS
European
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Research that mentions this SNP (1)

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Epigenetic and genetic variation in GATA5 is associated with gastric disease risk
AssociationN=289Sobota RS et al.(2016)· Human Genetics

A discovery and replication study of 130 and 159 Colombian patients examining genetic and epigenetic variation in GATA5 associated with gastric disease progression. Two synonymous SNPs in GATA5 (rs6061243 and rs6587239) were significantly associated with histopathology scores in dominant-effect models (p = 2.63×10⁻⁷ and 7.97×10⁻⁷, respectively, β = -0.86 and -0.82) and replicated in additive/dominant models. GATA5 promoter methylation was independently associated with disease progression (p = 0.001), and a significant SNP-by-methylation interaction indicated non-linear combined effects on gastric lesion severity.

Traits studied:Atrophic gastritisDysplasiaGastric cancerGastric disease progressionGastritisIntestinal metaplasia
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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