rs2099108
This variant is located in the GTF2A1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
schizophrenia
Liu J et al. “Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia.” Bmc Medicine 19(1):177 (2021)
Allele C
OR 1.05
p 3.0e-8
N 143,438
Meta-analysisLarge GWAS
multi-ancestry
About GTF2A1
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]
View all GTF2A1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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