rs2154481
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Alzheimer disease
Bellenguez C et al. “New insights into the genetic etiology of Alzheimer's disease and related dementias.” Nature Genetics 54(4):412-436 (2022)
Allele C
OR 0.95
p 1.0e-12
N 487,511
Large GWAS
European
Lake J et al. “Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease.” Molecular Psychiatry 28(7):3121-3132 (2023)
Allele C
OR —
p 1.0e-11
N 644,188
Meta-analysisLarge GWAS
multi-ancestry
Dalmasso MC et al. “The first genome-wide association study in the Argentinian and Chilean populations identifies shared genetics with Europeans in Alzheimer's disease.” Alzheimer's & Dementia : the Journal of the Alzheimer's Association 20(2):1298-1308 (2024)
Allele C
OR 0.95
p 1.0e-9
N 488,904
Large GWAS
multi-ancestry
de Rojas I et al. “Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.” Nature Communications 12(1):3417 (2021)
Allele C
OR 0.95
p 1.0e-11
N 451,469
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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