rs2221593
This variant is located in the BATF3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
leprosy
Liu H et al. “Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.” Nature Genetics 47(3):267-71 (2015)
Allele T
OR 1.15
p 3.0e-8
N 8,060
Large GWAS
East Asian
About BATF3
This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
View all BATF3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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