Trait
SNPs associated with Leprosy
41 genetic variants across 16 genes have been associated with Leprosy in published research. Key genes include ADGB, BATF3, C1orf141.
Associated variants41 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs10100465 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs55894533 | — | GWAS association (p=5.0e-11) | Meta-analysis |
| rs4720118 | — | GWAS association (p=4.0e-10) | Meta-analysis |
| rs6807915 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs9271100 | — | GWAS association (p=8.0e-95) | Large GWAS |
| rs9567307 | — | GWAS association (p=1.0e-93) | Large GWAS |
| rs2270368 | SNX20 | GWAS association (p=1.0e-67) | Large GWAS |
| rs3764147 | LACC1 | GWAS association (p=4.0e-54) | Large GWAS |
| rs9271011 | — | GWAS association (p=4.0e-50) | Large GWAS |
| rs4366152 | TNFSF15 | GWAS association (p=9.0e-42) | Large GWAS |
| rs9302752 | — | GWAS association (p=4.0e-40) | Large GWAS |
| rs383592 | — | GWAS association (p=2.0e-35) | Large GWAS |
| rs2024825 | C1orf141 | GWAS association (p=4.0e-33) | Large GWAS |
| rs602875 | — | GWAS association (p=5.0e-27) | Large GWAS |
| rs76886731 | IL1RL1 | GWAS association (p=2.0e-23) | Large GWAS |
| rs13220141 | — | GWAS association (p=1.0e-22) | Large GWAS |
| rs10817678 | — | GWAS association (p=1.0e-22) | Large GWAS |
| rs160451 | — | GWAS association (p=1.0e-21) | Large GWAS |
| rs6863015 | — | GWAS association (p=2.0e-21) | Large GWAS |
| rs6478108 | TNFSF15 | GWAS association (p=3.0e-21) | Large GWAS |
| rs42490 | RIPK2 | GWAS association (p=1.0e-16) | Large GWAS |
| rs3187964 | HLA-DQA1 | GWAS association (p=8.0e-16) | Large GWAS |
| rs77061563 | LOC105371082 | GWAS association (p=6.0e-15) | Large GWAS |
| rs2275606 | ADGB | GWAS association (p=4.0e-14) | Large GWAS |
| rs663743 | CCDC88B | GWAS association (p=9.0e-14) | Large GWAS |
| rs114598080 | — | GWAS association (p=9.0e-13) | Large GWAS |
| rs40457 | RIPK2 | GWAS association (p=1.0e-12) | Large GWAS |
| rs39761 | RIPK2 | GWAS association (p=1.0e-12) | Large GWAS |
| rs58600253 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs3762318 | C1orf141 | GWAS association (p=3.0e-11) | Large GWAS |
| rs16948876 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs1265048 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs13215778 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs10414149 | SIGLEC5 | GWAS association (p=3.0e-09) | Large GWAS |
| rs4921493 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs2015583 | MFSD13A | GWAS association (p=9.0e-09) | Large GWAS |
| rs73058713 | CDH18 | GWAS association (p=1.0e-08) | Large GWAS |
| rs10817758 | DELEC1 | GWAS association (p=1.0e-08) | Large GWAS |
| rs2221593 | BATF3 | GWAS association (p=3.0e-08) | Large GWAS |
| rs1801133 | MTHFR | GWAS association (p=3.0e-08) | Large GWAS |
| rs114231265 | — | GWAS association (p=4.0e-08) | Small GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.