rs2275606
This is a upstream gene variant variant in the ADGB gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
leprosy
Zhang F et al. “Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.” Nature Genetics 43(12):1247-51 (2011)
Allele A
OR 1.30
p 4.0e-14
N 6,287
Large GWAS
East Asian
About ADGB
Predicted to enable several functions, including calcium-dependent cysteine-type endopeptidase activity; heme binding activity; and oxygen binding activity. Predicted to be involved in spermatid development. Predicted to be located in sperm flagellum. Predicted to be active in sperm annulus and sperm midpiece. [provided by Alliance of Genome Resources, Jul 2025]
View all ADGB variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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