rs2229169

This is a synonymous variant in the ADRA2B gene — it does not change the protein's amino acid sequence.

Research that mentions this SNP (1)

The correlation between SNPs within the gene of adrenergic receptor and neuropeptide Y and risk of cervical vertigo
AssociationN=420Jianlong Han et al.(2018)· Journal of Clinical Laboratory Analysis

Case-control study of 216 cervical vertigo patients and 204 controls identifying SNPs in ADRA1A, ADRB1, ADRB2, and NPY genes significantly associated with cervical vertigo risk (ORs 0.62-2.07) and clinical prognosis markers (JOA score and recovery rate). ADRA1A rs3802241 showed OR=2.07 for disease risk and protective effect on prognosis; NPY variants predicted recovery outcomes.

Traits studied:Cervical vertigoInferior cervical vertigoSuperior cervical vertigoVertebral artery blood flow

About ADRA2B

This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. [provided by RefSeq, Apr 2014]

View all ADRA2B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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