rs2268361
This variant is located in the FSHR gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
polycystic ovary syndrome
Shi Y et al. “Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.” Nature Genetics 44(9):1020-5 (2012)
Allele C
OR 1.15
p 1.0e-12
N 5,255
Large GWAS
East Asian
About FSHR
The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
View all FSHR variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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