rs2274784

This is a intron variant variant in the HSDL2 gene.

▶

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

hip bone mineral density, hip bone size

Zhang H et al. “Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis.” Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the Usa 31(9):1691-1701 (2020)

Allele G

OR —

p 2.0e-8

N 6,175

Large GWAS

multi-ancestry

About HSDL2

Predicted to enable oxidoreductase activity. Involved in cholesterol homeostasis. Located in mitochondrion and peroxisome. [provided by Alliance of Genome Resources, Jul 2025]

View all HSDL2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…