rs2276220
This variant is located in the JAM2 gene.
▶ClinVar annotation
Benign★★★☆
2 submitters1 publicationAbout JAM2
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]
View all JAM2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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