rs2289081

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Barrett's esophagus

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele G

OR 0.10

p 2.0e-16

N 446,841

Major Consortium StudyLarge GWAS

European

pulse pressure measurement

Warren HR et al. “Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.” Nature Genetics 49(3):403-415 (2017)

Allele C

OR 0.22

p 6.0e-12

N 140,886

Large GWAS

European

diverticular disease

Wu Y et al. “150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.” Cell Genomics 3(7):100326 (2023)

Allele C

OR 0.03

p 3.0e-9

N 454,768

Large GWAS

European

prostate cancer

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele G

OR 0.09

p 1.0e-21

N 367,640

Major Consortium StudyLarge GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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