Trait
SNPs associated with Prostate cancer
162 genetic variants across 58 genes have been associated with Prostate cancer in published research. Key genes include ANO7, ATM, ATP5MC1.
Associated variants162 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs138213197 | HOXB13 | Higher prostate cancer risk in carriers | Meta-analysis |
| rs6983267 | CASC8 | Increased prostate cancer risk via MYC enhancer | Meta-analysis |
| rs1979277 | SHMT1 | Increased prostate cancer risk | Meta-analysis |
| rs17879961 | CHEK2 | Increased prostate cancer risk | Meta-analysis |
| rs1695 | GSTP1 | Increased prostate cancer risk | Meta-analysis |
| rs731236 | VDR | Increased prostate cancer risk in Asian and African American men | Meta-analysis |
| rs1800795 | IL6 | Increased prostate cancer susceptibility | Meta-analysis |
| rs4582524 | — | GWAS association (p=3.0e-128) | Major Consortium Study |
| rs72725854 | — | GWAS association (p=7.0e-97) | Major Consortium Study |
| rs12417087 | LOC105369367 | GWAS association (p=1.0e-95) | Major Consortium Study |
| rs995433 | LOC107986930 | GWAS association (p=1.0e-50) | Major Consortium Study |
| rs8071558 | — | GWAS association (p=4.0e-50) | Major Consortium Study |
| rs58235267 | — | GWAS association (p=4.0e-45) | Major Consortium Study |
| rs4919743 | KRT8 | GWAS association (p=9.0e-36) | Major Consortium Study |
| rs10486567 | JAZF1 | GWAS association (p=1.0e-34) | Major Consortium Study |
| rs77171792 | LINC00506 | GWAS association (p=1.0e-30) | Major Consortium Study |
| rs10840606 | — | GWAS association (p=9.0e-30) | Major Consortium Study |
| rs74461567 | — | GWAS association (p=9.0e-27) | Major Consortium Study |
| rs7591218 | — | GWAS association (p=7.0e-25) | Major Consortium Study |
| rs7611694 | SIDT1 | GWAS association (p=2.0e-24) | Major Consortium Study |
| rs72725879 | — | GWAS association (p=5.0e-24) | Major Consortium Study |
| rs4802297 | — | GWAS association (p=5.0e-24) | Major Consortium Study |
| rs11672691 | PCAT19 | Higher overall prostate cancer risk | Major Consortium Study |
| rs7808528 | — | GWAS association (p=5.0e-23) | Major Consortium Study |
| rs339351 | — | GWAS association (p=7.0e-22) | Major Consortium Study |
| rs2701109 | — | GWAS association (p=9.0e-21) | Major Consortium Study |
| rs9369290 | FOXP4 | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs7130881 | LOC105369367 | GWAS association (p=7.0e-20) | Major Consortium Study |
| rs4682495 | SIDT1 | GWAS association (p=5.0e-19) | Major Consortium Study |
| rs6557259 | — | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs13215045 | — | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs6853490 | — | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs331000 | — | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs2028900 | MAT2A | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs2926533 | — | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs6860961 | — | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs1771723 | — | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs2955117 | — | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs943559 | — | GWAS association (p=8.0e-14) | Major Consortium Study |
| rs201059790 | BCL2L11 | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs58223447 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs12027783 | SLC39A1 | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs11568818 | MMP7 | GWAS association (p=6.0e-13) | Major Consortium Study |
| rs965454 | C14orf39 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs1012568 | SUGCT | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs17804499 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs1990613 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs2949817 | TNS3 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs11635184 | MAP2K1 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs35477237 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs11239542 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs4924500 | RAD51 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs12213664 | SESN1 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs5759167 | — | GWAS association (p=7.0e-43) | Major Consortium Study |
| rs10007915 | — | GWAS association (p=1.0e-34) | Major Consortium Study |
| rs2242652 | TERT | GWAS association (p=7.0e-41) | Major Consortium Study |
| rs78416326 | — | GWAS association (p=1.0e-38) | Major Consortium Study |
| rs1058319 | — | GWAS association (p=7.0e-23) | Major Consortium Study |
| rs62113212 | KLK3 | GWAS association (p=8.0e-58) | Major Consortium Study |
| rs9979885 | — | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs3105751 | — | GWAS association (p=2.0e-30) | Major Consortium Study |
| rs7923435 | — | GWAS association (p=2.0e-30) | Major Consortium Study |
| rs2260801 | — | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs56222401 | — | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs12941683 | RNF227 | GWAS association (p=2.0e-20) | Major Consortium Study |
| rs2002731 | HNF1B | GWAS association (p=2.0e-37) | Major Consortium Study |
| rs3753639 | — | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs2289081 | — | GWAS association (p=1.0e-24) | Major Consortium Study |
| rs77559646 | ANO7 | GWAS association (p=3.0e-26) | Major Consortium Study |
| rs12655062 | CTD-2194D22.4 | GWAS association (p=2.0e-27) | Major Consortium Study |
| rs77541621 | — | GWAS association (p=2.0e-44) | Large GWAS |
| rs13255059 | — | GWAS association (p=9.0e-43) | Large GWAS |
| rs1456315 | PRNCR1 | GWAS association (p=4.0e-42) | Large GWAS |
| rs188140481 | — | GWAS association (p=4.0e-40) | Large GWAS |
| rs138042437 | CASC19 | GWAS association (p=1.0e-37) | Large GWAS |
| rs10908278 | — | GWAS association (p=5.0e-35) | Large GWAS |
| rs11651052 | — | GWAS association (p=4.0e-34) | Large GWAS |
| rs10993994 | MSMB | GWAS association (p=1.0e-32) | Large GWAS |
| rs530497867 | ATP5MC1 | GWAS association (p=5.0e-32) | Large GWAS |
| rs11228580 | — | GWAS association (p=3.0e-31) | Large GWAS |
| rs76765083 | — | GWAS association (p=3.0e-29) | Large GWAS |
| rs10743180 | — | GWAS association (p=3.0e-24) | Large GWAS |
| rs4646284 | — | GWAS association (p=1.0e-22) | Large GWAS |
| rs10956359 | — | GWAS association (p=2.0e-21) | Large GWAS |
| rs7837051 | — | GWAS association (p=9.0e-21) | Large GWAS |
| rs11599333 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs182352457 | LOC105375751 | GWAS association (p=3.0e-19) | Large GWAS |
| rs13274763 | — | GWAS association (p=5.0e-19) | Large GWAS |
| rs576161544 | LINC02086 | GWAS association (p=2.0e-18) | Large GWAS |
| rs13265330 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs568360281 | CDK5RAP3 | GWAS association (p=4.0e-18) | Large GWAS |
| rs4512771 | — | GWAS association (p=4.0e-18) | Large GWAS |
| rs11228501 | — | GWAS association (p=5.0e-18) | Large GWAS |
| rs61307529 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs185055152 | SKAP1 | GWAS association (p=2.0e-17) | Large GWAS |
| rs554574584 | COPZ2 | GWAS association (p=2.0e-17) | Large GWAS |
| rs559612720 | SKAP1 | GWAS association (p=2.0e-16) | Large GWAS |
| rs148511027 | — | GWAS association (p=7.0e-16) | Large GWAS |
| rs147567323 | CCAT1 | GWAS association (p=2.0e-15) | Large GWAS |
| rs146569428 | — | GWAS association (p=2.0e-14) | Large GWAS |
Showing the top 100 of 162 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.