rs72725879
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
prostate carcinoma
Wang A et al. “Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.” Nature Genetics 55(12):2065-2074 (2023)
Allele T
OR 1.26
p —
N 944,762
Large GWAS
multi-ancestry
Conti DV et al. “Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.” Nature Genetics 53(1):65-75 (2021)
Allele T
OR 1.29
p 1.0e-90
N 234,253
Meta-analysisLarge GWAS
multi-ancestry
Ishigaki K et al. “Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.” Nature Genetics 52(7):669-679 (2020)
Allele T
OR 1.61
p 3.0e-107
N 109,347
Large GWAS
East Asian
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.50
p 1.0e-115
N 90,332
Large GWAS
East Asian
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.34
p 1.0e-29
N 53,167
Major Consortium StudyLarge GWAS
Hispanic or Latin American
Hoffmann TJ et al. “A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.” Cancer Discovery 5(8):878-91 (2015)
Allele T
OR 1.92
p 3.0e-8
N 46,378
Large GWAS
multi-ancestry
prostate cancer
Janivara R et al. “Heterogeneous genetic architectures of prostate cancer susceptibility in sub-Saharan Africa.” Nature Genetics 56(10):2093-2103 (2024)
Allele T
OR 0.35
p 5.0e-24
N 7,472
Large GWAS
Sub-Saharan African
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.34
p 7.0e-15
N 26,428
Major Consortium StudyLarge GWAS
Hispanic or Latin American
prostate specific antigen amount
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.05
p 8.0e-15
N 72,792
Major Consortium StudyLarge GWAS
African American or Afro-Caribbean
Lin X et al. “A Germline Variant at 8q24 Contributes to the Serum p2PSA Level in a Chinese Prostate Biopsy Cohort.” Frontiers in Oncology 11:753920 (2021)
Allele C
OR 0.14
p 2.0e-9
N 886
Small GWAS
East Asian
urinary system disease
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.08
p 3.0e-12
N 104,575
Major Consortium StudyLarge GWAS
African American or Afro-Caribbean
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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