rs229533
This is a upstream gene variant variant in the C1QTNF6 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
type 2 diabetes mellitus
Márquez A et al. “Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations.” Genome Medicine 10(1):97 (2018)
Allele C
OR 1.14
p 7.0e-9
N 28,978
Meta-analysisLarge GWAS
European
type 1 diabetes mellitus
Onengut-Gumuscu S et al. “Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.” Nature Genetics 47(4):381-6 (2015)
Allele C
OR 1.11
p 2.0e-8
N 21,526
Large GWAS
European
About C1QTNF6
Enables identical protein binding activity. Predicted to be located in extracellular region and membrane. Predicted to be part of collagen trimer. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]
View all C1QTNF6 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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