rs2305411

This is a intron variant variant in the AQR gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

neuroticism measurement

Nagel M et al. “Genome-wide association study of the sensitivity to environmental stress and adversity neuroticism cluster.” Acta Psychiatrica Scandinavica 141(5):476-478 (2020)

Allele C

OR —

β 0.015

p 4.0e-9

N 351,827

Large GWAS

European

About AQR

Enables 3'-5' RNA helicase activity and single-stranded RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part of U2-type catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Jul 2025]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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