rs2381401
This is a regulatory region variant variant in the ARHGAP15 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
systemic lupus erythematosus
Wang YF et al. “Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups.” Nature Communications 12(1):772 (2021)
Allele T
OR 1.15
p 2.0e-9
N 25,268
Large GWAS
multi-ancestry
About ARHGAP15
RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]
View all ARHGAP15 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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