rs2413887

This is a upstream gene variant variant in the CTXN2 gene.

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

benign neoplasm of eye

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.52
p 4.0e-21
N 58,987
Major Consortium StudyLarge GWAS
Hispanic or Latin American

skin cancer

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.31
p 2.0e-12
N 58,901
Major Consortium StudyLarge GWAS
Hispanic or Latin American

Dermatochalasis

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.26
p 3.0e-11
N 625,298
Major Consortium StudyLarge GWAS
multi-ancestry

About CTXN2

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all CTXN2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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