Trait
SNPs associated with Skin cancer
72 genetic variants across 29 genes have been associated with Skin cancer in published research. Key genes include CDKN2B-AS1, CECR2, CLPTM1L.
Associated variants72 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12203592 | IRF4 | Increased risk of non-melanoma skin cancer | Meta-analysis |
| rs6059655 | RALY | GWAS association (p=2.0e-227) | Major Consortium Study |
| rs12350739 | — | GWAS association (p=1.0e-69) | Major Consortium Study |
| rs7582362 | FLACC1 | GWAS association (p=4.0e-56) | Major Consortium Study |
| rs56300457 | — | GWAS association (p=1.0e-46) | Major Consortium Study |
| rs10962650 | — | GWAS association (p=1.0e-44) | Major Consortium Study |
| rs7640550 | — | GWAS association (p=2.0e-43) | Major Consortium Study |
| rs113663016 | RCC2 | GWAS association (p=6.0e-38) | Major Consortium Study |
| rs55716899 | — | GWAS association (p=6.0e-35) | Major Consortium Study |
| rs75507031 | FLACC1 | GWAS association (p=3.0e-33) | Major Consortium Study |
| rs383009 | CLPTM1L | GWAS association (p=4.0e-32) | Major Consortium Study |
| rs3927680 | — | GWAS association (p=1.0e-30) | Major Consortium Study |
| rs13076312 | LPP | GWAS association (p=3.0e-27) | Major Consortium Study |
| rs35480566 | — | GWAS association (p=5.0e-27) | Major Consortium Study |
| rs6679677 | PHTF1 | GWAS association (p=3.0e-26) | Major Consortium Study |
| rs78378222 | TP53 | GWAS association (p=3.0e-25) | Major Consortium Study |
| rs78267753 | — | GWAS association (p=1.0e-24) | Major Consortium Study |
| rs1426654 | SLC24A5 | GWAS association (p=7.0e-24) | Major Consortium Study |
| rs214757 | TGM3 | GWAS association (p=1.0e-23) | Major Consortium Study |
| rs10425559 | — | GWAS association (p=2.0e-23) | Major Consortium Study |
| rs381949 | CLPTM1L | GWAS association (p=3.0e-23) | Major Consortium Study |
| rs13079741 | — | GWAS association (p=6.0e-23) | Major Consortium Study |
| rs9271499 | — | GWAS association (p=8.0e-22) | Major Consortium Study |
| rs111932154 | RCC2 | GWAS association (p=9.0e-22) | Major Consortium Study |
| rs61893460 | — | GWAS association (p=6.0e-21) | Major Consortium Study |
| rs10093547 | — | GWAS association (p=9.0e-19) | Major Consortium Study |
| rs7508601 | — | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs4977753 | CDKN2B-AS1 | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs2776353 | — | GWAS association (p=5.0e-18) | Major Consortium Study |
| rs1708302 | JAZF1 | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs3116521 | — | GWAS association (p=5.0e-17) | Major Consortium Study |
| rs182533474 | JAZF1 | GWAS association (p=8.0e-17) | Major Consortium Study |
| rs79643549 | — | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs214787 | TGM3 | GWAS association (p=7.0e-16) | Major Consortium Study |
| rs1800440 | CYP1B1 | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs9265142 | — | GWAS association (p=2.0e-15) | Major Consortium Study |
| rs149617956 | MITF | GWAS association (p=8.0e-15) | Major Consortium Study |
| rs9549597 | — | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs4599845 | — | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs72928978 | TPCN2 | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs28884287 | RGS22 | GWAS association (p=4.0e-14) | Major Consortium Study |
| rs10424978 | — | GWAS association (p=5.0e-14) | Major Consortium Study |
| rs112840089 | LOC107986952 | GWAS association (p=7.0e-14) | Major Consortium Study |
| rs2737217 | — | GWAS association (p=9.0e-14) | Major Consortium Study |
| rs1591136 | CDKN2B-AS1 | GWAS association (p=1.0e-13) | Major Consortium Study |
| rs1635852 | JAZF1 | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs7939541 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs10995255 | LOC105378327 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs2413887 | CTXN2 | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs553246842 | CECR2 | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs5766574 | KIAA0930 | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs528086186 | OLFML2A | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs12523056 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs28668506 | HLA-H | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs16897870 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs730153 | RCC2 | GWAS association (p=9.0e-19) | Major Consortium Study |
| rs35782301 | — | GWAS association (p=1.0e-30) | Major Consortium Study |
| rs801109 | — | GWAS association (p=8.0e-19) | Major Consortium Study |
| rs3087243 | CTLA4 | GWAS association (p=2.0e-28) | Major Consortium Study |
| rs16891982 | SLC45A2 | GWAS association (p=1.0e-240) | Major Consortium Study |
| rs61447909 | LINC01149 | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs114420104 | — | GWAS association (p=2.0e-22) | Major Consortium Study |
| rs72928038 | — | GWAS association (p=7.0e-55) | Major Consortium Study |
| rs204295 | — | GWAS association (p=4.0e-30) | Major Consortium Study |
| rs117132860 | — | GWAS association (p=6.0e-25) | Major Consortium Study |
| rs117744081 | — | GWAS association (p=1.0e-37) | Major Consortium Study |
| rs10905480 | — | GWAS association (p=7.0e-19) | Major Consortium Study |
| rs1126809 | TYR | GWAS association (p=5.0e-165) | Major Consortium Study |
| rs11170164 | KRT5 | GWAS association (p=1.0e-46) | Major Consortium Study |
| rs9549316 | — | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs1805007 | MC1R | GWAS association (p=8.0e-269) | Major Consortium Study |
| rs62211989 | — | GWAS association (p=6.0e-139) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.