CLPTM1L
CLPTM1 like
Summary
The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015]
Known Variants69 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs3816659 | 5:1,317,820 | A/C | — | — |
| rs372391081 | 5:1,318,490 | C/T | — | likely benign |
| rs375483144 | 5:1,318,504 | G/A | — | uncertain significance |
| rs763725767 | 5:1,318,533 | A/G | — | uncertain significance |
| rs780423882 | 5:1,318,548 | C/T | — | uncertain significance |
| rs755487218 | 5:1,318,552 | T/C | — | uncertain significance |
| rs451360 | 5:1,319,680 | C/A | intron variant | benign |
| rs402710 | 5:1,320,722 | C/T | intron variant | — |
| rs1429340504 | 5:1,320,724 | C/T | — | likely benign |
| rs778022626 | 5:1,320,762 | C/T | — | uncertain significance |
| rs1480687325 | 5:1,320,767 | T/A | — | uncertain significance |
| rs401681 | 5:1,322,087 | C/T | intron variant | — |
| rs381949 | 5:1,322,468 | G/A | intron variant | — |
| rs115028409 | 5:1,322,993 | G/A | — | benign |
| rs142887696 | 5:1,323,034 | G/A | — | likely benign |
| rs13178866 | 5:1,323,212 | C/T | intron variant | — |
| rs202162399 | 5:1,323,920 | A/G | — | uncertain significance |
| rs200291959 | 5:1,323,945 | C/T | — | likely benign |
| rs780776403 | 5:1,323,947 | C/G | — | uncertain significance |
| rs414965 | 5:1,324,121 | G/A | intron variant | — |
| rs150678949 | 5:1,325,874 | C/T | — | benign |
| rs2477038296 | 5:1,325,886 | C/T | — | uncertain significance |
| rs781774544 | 5:1,325,920 | C/G | — | likely benign |
| rs383009 | 5:1,327,851 | C/G | — | — |
| rs367942927 | 5:1,330,386 | G/A | — | likely benign |
| rs557678777 | 5:1,330,411 | A/G | — | uncertain significance |
| rs1241577491 | 5:1,330,448 | C/T | — | uncertain significance |
| rs1452932685 | 5:1,330,482 | G/A | — | likely benign |
| rs1309849938 | 5:1,330,489 | C/T | — | uncertain significance |
| rs370348 | 5:1,331,219 | A/G | regulatory region variant | — |
| rs756050018 | 5:1,331,918 | C/A | — | uncertain significance |
| rs778645980 | 5:1,331,935 | T/C | — | uncertain significance |
| rs774508335 | 5:1,331,984 | G/C | — | uncertain significance |
| rs2447853 | 5:1,333,077 | A/G | regulatory region variant | — |
| rs2455393 | 5:1,333,231 | G/T | — | — |
| rs549961426 | 5:1,333,246 | G/T | — | — |
| rs769044531 | 5:1,334,411 | G/A | — | uncertain significance |
| rs773036012 | 5:1,334,416 | G/C | — | likely benign |
| rs1267158028 | 5:1,334,437 | G/C | — | uncertain significance |
| rs376389240 | 5:1,334,442 | A/G | — | uncertain significance |
| rs146400141 | 5:1,334,472 | C/T | — | uncertain significance |
| rs34536907 | 5:1,335,176 | C/T | — | benign |
| rs116659965 | 5:1,335,194 | G/A | — | benign |
| rs193920801 | 5:1,335,219 | C/T | — | uncertain significance |
| rs756950098 | 5:1,335,244 | C/T | — | uncertain significance |
| rs150993328 | 5:1,335,280 | G/A | — | benign |
| rs455433 | 5:1,336,243 | A/T | — | — |
| rs459961 | 5:1,337,106 | T/A | intron variant | — |
| rs1210883090 | 5:1,338,993 | A/G | — | uncertain significance |
| rs199834712 | 5:1,339,115 | G/A | — | likely benign |
| rs31487 | 5:1,341,101 | G/C | intron variant | — |
| rs200467747 | 5:1,341,803 | C/T | — | uncertain significance |
| rs893729101 | 5:1,341,823 | T/C | — | uncertain significance |
| rs762040634 | 5:1,341,903 | G/A | — | likely benign |
| rs773500864 | 5:1,341,913 | A/C | — | uncertain significance |
| rs751677876 | 5:1,341,930 | C/T | — | likely benign |
| rs1019362368 | 5:1,341,931 | G/A | — | uncertain significance |
| rs142160762 | 5:1,341,936 | A/G | — | likely benign |
| rs31489 | 5:1,342,714 | C/A | intron variant | — |
| rs31490 | 5:1,344,458 | G/A | splice region variant | — |
| rs144759255 | 5:1,344,498 | C/G | — | benign |
| rs764351570 | 5:1,344,503 | T/C | — | uncertain significance |
| rs200649005 | 5:1,344,509 | C/G | — | uncertain significance |
| rs750262013 | 5:1,344,529 | G/T | — | uncertain significance |
| rs751026995 | 5:1,344,538 | T/G | — | uncertain significance |
| rs551900097 | 5:1,344,824 | G/A | — | uncertain significance |
| rs149912646 | 5:1,344,835 | T/C | — | uncertain significance |
| rs76174234 | 5:1,344,843 | G/A | — | benign |
| rs376590693 | 5:1,344,895 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.