Trait
SNPs associated with Melanoma
65 genetic variants across 25 genes have been associated with Melanoma in published research. Key genes include ADGRV1, AFG3L1P, C11orf65.
Associated variants65 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1805007 | MC1R | GWAS association (p=2.0e-72) | Meta-analysis |
| rs6059655 | RALY | GWAS association (p=3.0e-38) | Meta-analysis |
| rs869330 | — | GWAS association (p=3.0e-35) | Meta-analysis |
| rs1126809 | TYR | GWAS association (p=6.0e-31) | Meta-analysis |
| rs31490 | CLPTM1L | GWAS association (p=1.0e-26) | Meta-analysis |
| rs16891982 | SLC45A2 | GWAS association (p=2.0e-20) | Meta-analysis |
| rs1885120 | MYH7B | GWAS association (p=2.0e-18) | Meta-analysis |
| rs958219 | — | GWAS association (p=8.0e-15) | Meta-analysis |
| rs12203592 | IRF4 | GWAS association (p=8.0e-15) | Meta-analysis |
| rs2413507 | — | GWAS association (p=1.0e-14) | Meta-analysis |
| rs183783391 | — | GWAS association (p=4.0e-14) | Meta-analysis |
| rs4268748 | DEF8 | GWAS association (p=1.0e-13) | Meta-analysis |
| rs139122788 | C11orf65 | GWAS association (p=3.0e-12) | Meta-analysis |
| rs443099 | MX2 | GWAS association (p=6.0e-12) | Meta-analysis |
| rs1800407 | OCA2 | GWAS association (p=7.0e-11) | Meta-analysis |
| rs6540842 | PTPN14 | GWAS association (p=2.0e-10) | Meta-analysis |
| rs9639279 | — | GWAS association (p=5.0e-10) | Meta-analysis |
| rs7907606 | — | GWAS association (p=6.0e-10) | Meta-analysis |
| rs6937555 | — | GWAS association (p=8.0e-10) | Meta-analysis |
| rs10979147 | — | GWAS association (p=2.0e-09) | Meta-analysis |
| rs13356727 | — | GWAS association (p=3.0e-09) | Meta-analysis |
| rs76798800 | — | GWAS association (p=4.0e-09) | Meta-analysis |
| rs117132860 | — | GWAS association (p=5.0e-09) | Meta-analysis |
| rs78378222 | TP53 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs6776157 | — | GWAS association (p=5.0e-08) | Meta-analysis |
| rs2228570 | VDR | Increased melanoma risk | Meta-analysis |
| rs35026726 | ZNF276 | GWAS association (p=4.0e-61) | Large GWAS |
| rs75570604 | — | GWAS association (p=7.0e-34) | Large GWAS |
| rs56238684 | PIGU | GWAS association (p=2.0e-33) | Large GWAS |
| rs871024 | — | GWAS association (p=6.0e-29) | Large GWAS |
| rs4408545 | — | GWAS association (p=1.0e-28) | Large GWAS |
| rs2425025 | — | GWAS association (p=4.0e-28) | Large GWAS |
| rs258322 | CDK10 | GWAS association (p=3.0e-27) | Large GWAS |
| rs4499232 | — | GWAS association (p=9.0e-26) | Large GWAS |
| rs4785763 | AFG3L1P | GWAS association (p=6.0e-22) | Large GWAS |
| rs17401449 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs35407 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs1204552 | — | GWAS association (p=3.0e-19) | Large GWAS |
| rs910873 | PIGU | GWAS association (p=1.0e-15) | Large GWAS |
| rs1393350 | TYR | GWAS association (p=2.0e-14) | Large GWAS |
| rs150260898 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs11813268 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs62389423 | — | GWAS association (p=9.0e-14) | Large GWAS |
| rs117382825 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs498136 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs16953002 | FTO | GWAS association (p=4.0e-12) | Large GWAS |
| rs139996880 | TERT | GWAS association (p=7.0e-12) | Large GWAS |
| rs55797833 | — | GWAS association (p=7.0e-12) | Large GWAS |
| rs1805008 | MC1R | GWAS association (p=1.0e-11) | Large GWAS |
| rs10739221 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs7412746 | CTXND2 | GWAS association (p=9.0e-11) | Large GWAS |
| rs3761444 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs13016963 | FLACC1 | GWAS association (p=9.0e-10) | Large GWAS |
| rs2995264 | STN1 | GWAS association (p=2.0e-09) | Large GWAS |
| rs6750047 | — | GWAS association (p=7.0e-09) | Large GWAS |
| rs1636744 | — | GWAS association (p=7.0e-09) | Large GWAS |
| rs112584165 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs12186662 | ADGRV1 | GWAS association (p=1.0e-08) | Large GWAS |
| rs11442196 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs736264 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs45430 | MX2 | GWAS association (p=3.0e-08) | Large GWAS |
| rs401681 | CLPTM1L | GWAS association (p=3.0e-08) | Large GWAS |
| rs9818780 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs6914598 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs187843643 | LINC02218 | GWAS association (p=4.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.